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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Roger Clemens# | 3887.0 | 1984-2001 | |
| 2 | Greg Maddux# | 3551.0 | 1986-2001 | |
| 3 | Tom Glavine# | 3120.0 | 1987-2001 | |
| 4 | Chuck Finley# | 3006.0 | 1986-2001 | |
| 5 | Kevin Brown# | 2776.0 | 1986-2001 | |
| 6 | Randy Johnson# | 2748.0 | 1988-2001 | |
| 7 | Mike Morgan# | 2738.0 | 1978-2001 | |
| 8 | John Smoltz# | 2473.0 | 1988-2001 | |
| 9 | Andy Benes# | 2408.0 | 1989-2001 | |
| 10 | David Wells# | 2407.0 | 1987-2001 | |
| 11 | John Burkett# | 2293.0 | 1987-2001 | |
| 12 | Jamie Moyer# | 2292.0 | 1986-2001 | |
| 13 | Kevin Appier# | 2291.0 | 1989-2001 | |
| 14 | Mike Mussina# | 2238.0 | 1991-2001 | |
| 15 | Terry Mulholland# | 2212.0 | 1986-2001 | |
| 16 | Greg Swindell# | 2200.0 | 1986-2001 | |
| 17 | Todd Stottlemyre# | 2171.0 | 1988-2000 | |
| 18 | Curt Schilling# | 2158.0 | 1988-2001 | |
| 19 | Scott Erickson# | 2106.0 | 1990-2000 | |
| 20 | Darryl Kile# | 2080.0 | 1991-2001 | |
| 21 | Kenny Rogers# | 2049.0 | 1989-2001 | |
| 22 | Charles Nagy# | 1893.0 | 1990-2001 | |
| 23 | Pat Hentgen# | 1812.0 | 1991-2001 | |
| 24 | Jose Rijo# | 1803.0 | 1984-2001 | |
| 25 | Pedro Astacio# | 1742.0 | 1992-2001 | |
| 26 | Pedro Martinez# | 1693.0 | 1992-2001 | |
| 27 | Denny Neagle# | 1690.0 | 1991-2001 | |
| 27 | Tom Gordon# | 1690.0 | 1988-2001 | |
| 27 | Al Leiter# | 1690.0 | 1987-2001 | |
| 30 | Jeff Fassero# | 1669.0 | 1991-2001 | |
| 31 | Andy Ashby# | 1554.0 | 1991-2001 | |
| 32 | Shane Reynolds# | 1548.0 | 1992-2001 | |
| 33 | Brad Radke# | 1537.0 | 1995-2001 | |
| 34 | Steve Trachsel# | 1520.0 | 1993-2001 | |
| 35 | Tim Wakefield# | 1512.0 | 1992-2001 | |
| 35 | Dave Burba# | 1512.0 | 1990-2001 | |
| 37 | Aaron Sele# | 1466.0 | 1993-2001 | |
| 38 | Mike Hampton# | 1463.0 | 1993-2001 | |
| 39 | Andy Pettitte# | 1449.0 | 1995-2001 | |
| 40 | Wilson Alvarez# | 1433.0 | 1989-1999 | |
| 41 | Frank Castillo# | 1426.0 | 1991-2001 | |
| 42 | Bobby Jones# | 1410.0 | 1993-2001 | |
| 43 | Jon Lieber# | 1369.0 | 1994-2001 | |
| 44 | Hideo Nomo# | 1348.0 | 1995-2001 | |
| 45 | Ismael Valdez# | 1295.0 | 1994-2001 | |
| 46 | Kirk Rueter# | 1269.0 | 1993-2001 | |
| 47 | Jesse Orosco# | 1234.0 | 1979-2001 | |
| 48 | Rick Reed# | 1222.0 | 1988-2001 | |
| 49 | Woody Williams# | 1209.0 | 1993-2001 | |
| 50 | Joey Hamilton# | 1205.0 | 1994-2001 | |
| 51 | Chan-ho Park# | 1183.0 | 1994-2001 | |
| 52 | Jose Mesa# | 1166.0 | 1987-2001 | |
| 53 | Dave Mlicki# | 1146.0 | 1992-2001 | |
| 54 | Sterling Hitchcock# | 1137.0 | 1992-2001 | |
| 55 | Rick Helling# | 1111.0 | 1994-2001 | |
| 56 | Esteban Loaiza# | 1102.0 | 1995-2001 | |
| 57 | Darren Oliver# | 1096.0 | 1993-2001 | |
| 58 | James Baldwin# | 1095.0 | 1995-2001 | |
| 59 | Mike Jackson# | 1086.0 | 1986-2001 | |
| 60 | Armando Reynoso# | 1078.0 | 1991-2001 | |
| 61 | Jose Lima# | 1069.0 | 1994-2001 | |
| 61 | Kent Mercker# | 1069.0 | 1989-2000 | |
| 63 | Jason Bere# | 1018.0 | 1993-2001 | |
| 64 | Dan Plesac# | 1002.0 | 1986-2001 | |
| 65 | Livan Hernandez# | 1000.0 | 1996-2001 | |
| 66 | Dustin Hermanson# | 997.0 | 1995-2001 | |
| 67 | Brian Anderson# | 996.0 | 1993-2001 | |
| 68 | Shawn Estes# | 990.0 | 1995-2001 | |
| 69 | Dennis Cook# | 987.0 | 1988-2001 | |
| 70 | Jason Schmidt# | 949.0 | 1995-2001 | |
| 71 | Omar Daal# | 943.0 | 1993-2001 | |
| 72 | Paul Quantrill# | 937.0 | 1992-2001 | |
| 73 | Bartolo Colon# | 913.0 | 1997-2001 | |
| 74 | Steve Sparks# | 903.0 | 1995-2001 | |
| 75 | Jamey Wright# | 901.0 | 1996-2001 | |
| 76 | Rheal Cormier# | 897.0 | 1991-2001 | |
| 77 | Jimmy Haynes# | 894.0 | 1995-2001 | |
| 78 | Mark Guthrie# | 888.0 | 1989-2001 | |
| 79 | Jeff Suppan# | 880.0 | 1995-2001 | |
| 80 | Chris Hammond# | 843.0 | 1990-1998 | |
| 81 | Donovan Osborne# | 840.0 | 1992-1999 | |
| 82 | Bob Wickman# | 828.0 | 1992-2001 | |
| 83 | Eric Milton# | 799.0 | 1998-2001 | |
| 84 | Robert Person# | 798.0 | 1995-2001 | |
| 85 | Chris Carpenter# | 797.0 | 1997-2001 | |
| 86 | Chris Haney# | 794.0 | 1991-2000 | |
| 87 | Mike Trombley# | 791.0 | 1992-2001 | |
| 88 | Brian Moehler# | 789.0 | 1996-2001 | |
| 89 | Kevin Millwood# | 787.0 | 1997-2001 | |
| 90 | Hipolito Pichardo# | 769.0 | 1992-2001 | |
| 91 | David Weathers# | 768.0 | 1991-2001 | |
| 91 | Javier Vazquez# | 768.0 | 1998-2001 | |
| 93 | Albie Lopez# | 763.0 | 1993-2001 | |
| 94 | Arthur Rhodes# | 759.0 | 1991-2001 | |
| 95 | Mike Stanton# | 745.0 | 1989-2001 | |
| 96 | Roberto Hernandez# | 723.0 | 1991-2001 | |
| 97 | Julian Tavarez# | 714.0 | 1993-2001 | |
| 98 | Russ Ortiz# | 710.0 | 1998-2001 | |
| 99 | Sidney Ponson# | 705.0 | 1998-2001 | |
| 100 | Glendon Rusch# | 699.0 | 1997-2001 |
