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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | SV | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Mariano Rivera# | 24 | 1995-2001 | |
| 2 | Mark Wohlers# | 10 | 1991-2001 | |
| 3 | Jose Mesa# | 6 | 1987-2001 | |
| 4 | Armando Benitez# | 4 | 1994-2001 | |
| 4 | Mike Jackson# | 4 | 1986-2001 | |
| 4 | Robb Nen# | 4 | 1993-2001 | |
| 4 | Kazuhiro Sasaki# | 4 | 2000-2001 | |
| 8 | Trevor Hoffman# | 3 | 1993-2001 | |
| 8 | Jason Isringhausen# | 3 | 1995-2001 | |
| 8 | Byung-hyun Kim# | 3 | 1999-2001 | |
| 8 | John Rocker# | 3 | 1998-2001 | |
| 8 | John Smoltz# | 3 | 1988-2001 | |
| 13 | Steve Kline# | 2 | 1997-2001 | |
| 13 | Jesse Orosco# | 2 | 1979-2001 | |
| 15 | Brian Anderson# | 1 | 1993-2001 | |
| 15 | Pedro Borbon# | 1 | 1992-2001 | |
| 15 | Roberto Hernandez# | 1 | 1991-2001 | |
| 15 | Greg Maddux# | 1 | 1986-2001 | |
| 15 | Ramiro Mendoza# | 1 | 1996-2001 | |
| 15 | Kevin Millwood# | 1 | 1997-2001 | |
| 15 | Mike Stanton# | 1 | 1989-2001 | |
| 15 | Mike Timlin# | 1 | 1991-2001 | |
| 15 | Dave Veres# | 1 | 1994-2001 | |
| 15 | Donne Wall# | 1 | 1995-2001 | |
| 25 | Paul Abbott# | 0 | 1990-2001 | |
| 25 | Antonio Alfonseca# | 0 | 1997-2001 | |
| 25 | Wilson Alvarez# | 0 | 1989-1999 | |
| 25 | Kevin Appier# | 0 | 1989-2001 | |
| 25 | Andy Ashby# | 0 | 1991-2001 | |
| 25 | Pedro Astacio# | 0 | 1992-2001 | |
| 25 | Danys Baez# | 0 | 2001-2001 | |
| 25 | James Baldwin# | 0 | 1995-2001 | |
| 25 | Lorenzo Barcelo# | 0 | 2000-2001 | |
| 25 | Miguel Batista# | 0 | 1992-2001 | |
| 25 | Alan Benes# | 0 | 1995-2001 | |
| 25 | Andy Benes# | 0 | 1989-2001 | |
| 25 | Jason Bere# | 0 | 1993-2001 | |
| 25 | Brian Boehringer# | 0 | 1995-2001 | |
| 25 | Chad Bradford# | 0 | 1998-2001 | |
| 25 | Troy Brohawn# | 0 | 2001-2001 | |
| 25 | Kevin Brown# | 0 | 1986-2001 | |
| 25 | Mark Buehrle# | 0 | 2000-2001 | |
| 25 | Dave Burba# | 0 | 1990-2001 | |
| 25 | John Burkett# | 0 | 1987-2001 | |
| 25 | Jose Cabrera# | 0 | 1997-2001 | |
| 25 | Randy Choate# | 0 | 2000-2001 | |
| 25 | Jason Christiansen# | 0 | 1995-2001 | |
| 25 | Roger Clemens# | 0 | 1984-2001 | |
| 25 | Bartolo Colon# | 0 | 1997-2001 | |
| 25 | Dennis Cook# | 0 | 1988-2001 | |
| 25 | Rheal Cormier# | 0 | 1991-2001 | |
| 25 | Nelson Cruz# | 0 | 1997-2001 | |
| 25 | Omar Daal# | 0 | 1993-2001 | |
| 25 | Sean DePaula# | 0 | 1999-2000 | |
| 25 | Octavio Dotel# | 0 | 1999-2001 | |
| 25 | Alan Embree# | 0 | 1992-2001 | |
| 25 | Scott Erickson# | 0 | 1990-2000 | |
| 25 | Shawn Estes# | 0 | 1995-2001 | |
| 25 | Jeff Fassero# | 0 | 1991-2001 | |
| 25 | Chuck Finley# | 0 | 1986-2001 | |
| 25 | Keith Foulke# | 0 | 1997-2001 | |
| 25 | Aaron Fultz# | 0 | 2000-2001 | |
| 25 | Rich Garces# | 0 | 1990-2001 | |
| 25 | Tom Glavine# | 0 | 1987-2001 | |
| 25 | Tom Gordon# | 0 | 1988-2001 | |
| 25 | Jason Grimsley# | 0 | 1989-2001 | |
| 25 | Mark Guthrie# | 0 | 1989-2001 | |
| 25 | John Halama# | 0 | 1998-2001 | |
| 25 | Joey Hamilton# | 0 | 1994-2001 | |
| 25 | Mike Hampton# | 0 | 1993-2001 | |
| 25 | Rick Helling# | 0 | 1994-2001 | |
| 25 | Pat Hentgen# | 0 | 1991-2001 | |
| 25 | Felix Heredia# | 0 | 1996-2001 | |
| 25 | Dustin Hermanson# | 0 | 1995-2001 | |
| 25 | Livan Hernandez# | 0 | 1996-2001 | |
| 25 | Orlando Hernandez# | 0 | 1998-2001 | |
| 25 | Erik Hiljus# | 0 | 1999-2001 | |
| 25 | Sterling Hitchcock# | 0 | 1992-2001 | |
| 25 | Darren Holmes# | 0 | 1990-2000 | |
| 25 | Bob Howry# | 0 | 1998-2001 | |
| 25 | Tim Hudson# | 0 | 1999-2001 | |
| 25 | Hideki Irabu# | 0 | 1997-2001 | |
| 25 | Mike James# | 0 | 1995-2001 | |
| 25 | Randy Johnson# | 0 | 1988-2001 | |
| 25 | Bobby Jones# | 0 | 1993-2001 | |
| 25 | Steve Karsay# | 0 | 1993-2001 | |
| 25 | Darryl Kile# | 0 | 1991-2001 | |
| 25 | Al Leiter# | 0 | 1987-2001 | |
| 25 | Cory Lidle# | 0 | 1997-2001 | |
| 25 | Kerry Ligtenberg# | 0 | 1997-2001 | |
| 25 | Jose Lima# | 0 | 1994-2001 | |
| 25 | Graeme Lloyd# | 0 | 1993-2001 | |
| 25 | Esteban Loaiza# | 0 | 1995-2001 | |
| 25 | Albie Lopez# | 0 | 1993-2001 | |
| 25 | Derek Lowe# | 0 | 1997-2001 | |
| 25 | Mike Magnante# | 0 | 1991-2001 | |
| 25 | Pat Mahomes# | 0 | 1992-2001 | |
| 25 | Matt Mantei# | 0 | 1995-2001 | |
| 25 | Jason Marquis# | 0 | 2000-2001 | |
| 25 | Tom Martin# | 0 | 1997-2001 |
