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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Sterling Hitchcock# | 12.03 | 1992-2001 | |
| 2 | Armando Benitez# | 10.68 | 1994-2001 | |
| 3 | Randy Johnson# | 10.59 | 1988-2001 | |
| 4 | Mark Wohlers# | 10.33 | 1991-2001 | |
| 5 | Jeff Nelson# | 10.27 | 1992-2001 | |
| 6 | Mike Mussina# | 9.99 | 1991-2001 | |
| 7 | Curt Schilling# | 9.49 | 1988-2001 | |
| 8 | Orlando Hernandez# | 8.74 | 1998-2001 | |
| 9 | Kevin Brown# | 8.46 | 1986-2001 | |
| 10 | John Smoltz# | 8.44 | 1988-2001 | |
| 11 | Roger Clemens# | 8.43 | 1984-2001 | |
| 12 | Jaret Wright# | 8.17 | 1997-2001 | |
| 13 | Todd Stottlemyre# | 8.10 | 1988-2000 | |
| 14 | Mike Stanton# | 7.81 | 1989-2001 | |
| 15 | Livan Hernandez# | 7.75 | 1996-2001 | |
| 16 | Al Leiter# | 7.62 | 1987-2001 | |
| 17 | Jose Mesa# | 7.53 | 1987-2001 | |
| 18 | Bartolo Colon# | 7.28 | 1997-2001 | |
| 19 | Mariano Rivera# | 7.18 | 1995-2001 | |
| 20 | David Wells# | 7.17 | 1987-2001 | |
| 21 | Kevin Millwood# | 7.12 | 1997-2001 | |
| 22 | Denny Neagle# | 7.07 | 1991-2001 | |
| 23 | Andy Benes# | 6.90 | 1989-2001 | |
| 24 | Mike Hampton# | 6.20 | 1993-2001 | |
| 25 | Tom Glavine# | 6.18 | 1987-2001 | |
| 26 | Greg Maddux# | 5.97 | 1986-2001 | |
| 27 | Charles Nagy# | 5.85 | 1990-2001 | |
| 28 | Scott Erickson# | 5.71 | 1990-2000 | |
| 29 | Darryl Kile# | 5.40 | 1991-2001 | |
| 30 | Andy Pettitte# | 5.00 | 1995-2001 | |
| 31 | Aaron Sele# | 4.21 | 1993-2001 |
