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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Randy Johnson# | 13.41 | 2001 | |
| 2 | Pedro Martinez# | 13.20 | 1999 | |
| 3 | Kerry Wood# | 12.58 | 1998 | |
| 4 | Randy Johnson# | 12.56 | 2000 | |
| 5 | Randy Johnson# | 12.35 | 1995 | |
| 6 | Randy Johnson# | 12.30 | 1997 | |
| 7 | Randy Johnson# | 12.12 | 1998 | |
| 8 | Randy Johnson# | 12.06 | 1999 | |
| 9 | Pedro Martinez# | 11.78 | 2000 | |
| 10 | Pedro Martinez# | 11.37 | 1997 | |
| 11 | Curt Schilling# | 11.29 | 1997 | |
| 12 | Kerry Wood# | 11.20 | 2001 | |
| 13 | Hideo Nomo# | 11.10 | 1995 | |
| 14 | Randy Johnson# | 10.86 | 1993 | |
| 15 | Randy Johnson# | 10.67 | 1994 | |
| 16 | Roger Clemens# | 10.39 | 1998 | |
| 17 | Randy Johnson# | 10.31 | 1992 | |
| 18 | Curt Schilling# | 10.27 | 2001 | |
| 19 | Randy Johnson# | 10.19 | 1991 | |
| 20 | Bartolo Colon# | 10.15 | 2000 | |
| 21 | Hideo Nomo# | 10.11 | 1997 | |
| 22 | Curt Schilling# | 10.05 | 1998 | |
| 23 | Hideo Nomo# | 10.00 | 2001 | |
| 24 | Roger Clemens# | 9.95 | 1997 | |
| 25 | Roger Clemens# | 9.92 | 1988 | |
| 26 | Andy Benes# | 9.87 | 1994 | |
| 27 | John Smoltz# | 9.79 | 1996 | |
| 28 | Pedro Martinez# | 9.67 | 1998 | |
| 29 | Roger Clemens# | 9.53 | 1996 | |
| 30 | John Smoltz# | 9.29 | 1998 | |
| 31 | Hideo Nomo# | 9.22 | 1996 | |
| 31 | Pedro Martinez# | 9.22 | 1996 | |
| 33 | John Smoltz# | 9.02 | 1995 | |
| 34 | Kevin Brown# | 9.00 | 1998 | |
| 34 | Darryl Kile# | 9.00 | 1996 | |
| 36 | Curt Schilling# | 8.93 | 1996 | |
| 36 | Jose Rijo# | 8.93 | 1994 | |
| 38 | Andy Benes# | 8.90 | 1997 | |
| 39 | Jose Rijo# | 8.89 | 1988 | |
| 40 | Roger Clemens# | 8.86 | 1994 | |
| 41 | Pedro Astacio# | 8.85 | 2000 | |
| 42 | Kevin Appier# | 8.82 | 1996 | |
| 43 | Todd Stottlemyre# | 8.80 | 1995 | |
| 44 | Mike Mussina# | 8.73 | 1997 | |
| 45 | Roger Clemens# | 8.70 | 2001 | |
| 46 | Al Leiter# | 8.65 | 2000 | |
| 46 | Chuck Finley# | 8.65 | 1995 | |
| 48 | Chan-ho Park# | 8.64 | 2000 | |
| 49 | Jeff Fassero# | 8.62 | 1996 | |
| 50 | Barry Zito# | 8.61 | 2001 | |
| 51 | Hideo Nomo# | 8.57 | 2000 | |
| 52 | Chuck Finley# | 8.54 | 1998 | |
| 53 | CC Sabathia# | 8.53 | 2001 | |
| 54 | Robert Person# | 8.52 | 2000 | |
| 55 | Chuck Finley# | 8.51 | 1997 | |
| 56 | Sterling Hitchcock# | 8.49 | 1999 | |
| 57 | John Smoltz# | 8.47 | 1997 | |
| 57 | Andy Benes# | 8.47 | 1995 | |
| 57 | Dave Burba# | 8.47 | 2000 | |
| 60 | Kevin Brown# | 8.45 | 2000 | |
| 60 | Tom Gordon# | 8.45 | 1989 | |
| 62 | Chuck Finley# | 8.44 | 1999 | |
| 63 | Roger Clemens# | 8.43 | 1986 | |
| 64 | Mike Mussina# | 8.42 | 2001 | |
| 65 | Kevin Millwood# | 8.41 | 1998 | |
| 66 | Randy Wolf# | 8.39 | 2001 | |
| 67 | Chan-ho Park# | 8.38 | 2001 | |
| 67 | Jason Bere# | 8.38 | 2001 | |
| 69 | Javier Vazquez# | 8.37 | 2001 | |
| 70 | Al Leiter# | 8.36 | 1996 | |
| 71 | Shane Reynolds# | 8.32 | 1995 | |
| 72 | Ryan Dempster# | 8.31 | 2000 | |
| 73 | Todd Stottlemyre# | 8.28 | 1998 | |
| 73 | Roger Clemens# | 8.28 | 2000 | |
| 75 | Kevin Appier# | 8.27 | 1995 | |
| 76 | Roger Clemens# | 8.24 | 1990 | |
| 77 | Jon Lieber# | 8.23 | 1999 | |
| 78 | Hideo Nomo# | 8.22 | 1999 | |
| 79 | Roger Clemens# | 8.18 | 1987 | |
| 79 | Jose Rijo# | 8.18 | 1986 | |
| 81 | Roger Clemens# | 8.17 | 1989 | |
| 81 | Aaron Sele# | 8.17 | 1999 | |
| 83 | Pedro Astacio# | 8.15 | 1999 | |
| 84 | Bartolo Colon# | 8.14 | 2001 | |
| 85 | Chuck Finley# | 8.13 | 1996 | |
| 86 | Al Leiter# | 8.11 | 1998 | |
| 87 | Shawn Estes# | 8.10 | 1997 | |
| 87 | Javier Vazquez# | 8.10 | 2000 | |
| 89 | Kevin Millwood# | 8.09 | 1999 | |
| 90 | Sterling Hitchcock# | 8.06 | 1998 | |
| 90 | Tom Gordon# | 8.06 | 1990 | |
| 90 | Shane Reynolds# | 8.06 | 1998 | |
| 90 | Chan-ho Park# | 8.06 | 1999 | |
| 94 | Tony Armas# | 8.05 | 2001 | |
| 95 | Pedro Martinez# | 8.04 | 1995 | |
| 96 | Roger Clemens# | 7.99 | 1991 | |
| 97 | Todd Stottlemyre# | 7.96 | 1997 | |
| 98 | Mike Mussina# | 7.95 | 2000 | |
| 98 | Randy Johnson# | 7.95 | 1990 | |
| 100 | Jose Rijo# | 7.94 | 1993 |
